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Inclisiran is indicated in adults with primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia, as an adjunct to diet:
- in combination with a statin or statin with other lipid-lowering therapies in patients unable to reach LDL-C goals with the maximum tolerated dose of a statin, or
- alone or in combination with other lipid-lowering therapies in patients who are statin-intolerant, or for whom a statin is contraindicated.1
Leqvio® is not reimbursed in Ireland at this time.
Explore our growing repository of resources designed to provide useful information on Leqvio® and other relevant topics for healthcare professionals treating patients with ASCVD.
LEQVIO® DOSING AND ADMINISTRATION: ‘HOW TO’ GUIDE
Key steps and important information you need to know about LEQVIO® dosing and administration on one page.
GUIDE TO USING LEQVIO®
A short video explaining how to administer Leqvio®, including step-by-step instructions for injection.
LEQVIO® MOA VIDEO
A video displaying the mechanism of action of Leqvio®, the first and only siRNA LDL-C-lowering therapy.1,3,4
ELEVATED LDL-C: THE IMPORTANCE OF EARLY INTERVENTION
A short animation highlighting the consequences of long-term exposure to persistently elevated LDL-C.
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ASCVD, atherosclerotic cardiovascular disease; HCP, healthcare professional; LDL-C, low-density lipoprotein cholesterol; MOA, mechanism of action; siRNA, small interfering ribonucleic acid.
References
- Leqvio® Summary of Product Characteristics. Accessed August 2022 at www.ema.europe.eu
- Ray KK et al. N Engl J Med 2020;382(16):1507–1519.
- Stoekenbroek RM et al. Future Cardiol 2018;14(6):433–442.
- Klinovski M et al. CADTH Issues in Emerging Health Technologies, 2019. Canadian Agency for Drugs and Technologies in Health.