Prescribe ENTRESTO® to act directly on the heart and improve its structure and function1
Unbalanced, NPS and RAAS are 2 critical pathways that contribute to HFrEF and loss of pumping function2
Watch the mechanism of action video below to gain a deeper understanding of ENTRESTO’s complementary actions3
ENTRESTO is indicated in adult patients for the treatment of symptomatic chronic heart failure with reduced ejection fraction.3
ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNI, angiotensin receptor neprilysin inhibitor; RAAS, renin-angiotensin-aldosterone system.
- Januzzi JL Jr, et al. JAMA 2019;322(11):1085–1095.
- Diez J et al. Eur J Heart Fail 2016; 19 (2) 167-176.
- ENTRESTO Summary of Product Characteristics. Accessed December 2021 at www.medicines.ie
- Desai AS, et al. JAMA 2019;322(11):1077–1084.
- Wang Y, et al. J Am Heart Assoc 2019;8(13):e012272.